Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777065 | 0.81 | CYP2D6 (0.37) | PDK2CYP2D6CYP2C9MLNRNR1I2 | |
| SCHEMBL20415566 | 0.79 | LIPG (0.46) | NR1H2NR1H3LIPGPDK2ALOX5 | |
| SCHEMBL28192476 | 0.79 | PDK2 (0.43) | LIPGPDK2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL3205351 | 0.76 | LIPG (0.45) | NR1H2NR1H3LIPGELANECTSG | |
| SCHEMBL30287526 | 0.76 | LIPG (0.45) | NR1H2NR1H3LIPGELANECTSG | |
| SCHEMBL28362254 | 0.76 | LIPG (0.45) | NR1H2NR1H3LIPGCYP2D6ELANE | |
| SCHEMBL1879231 | 0.76 | THRB (0.54) | NR1H2NR1H3PDK2CYP2D6ELANE | |
| SCHEMBL27778176 | 0.76 | ELANE (0.36) | NR1H2NR1H3LIPGPDK2CYP2D6 | |
| SCHEMBL2701240 | 0.73 | LIPG (0.50) | NR1H2NR1H3LIPGCYP2D6CYP3A4 | |
| SCHEMBL2009831 | 0.73 | PDK2 (0.38) | PDK2CYP2D6CYP2C9MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490008-A | Fused heterocyclic compound and organic light emitting device | CANON KK (JP) | 2009-07-22 | — | — | CN | disclosed |