SCHEMBL27778367

SCHEMBL27778367

O=COCCc1cc2c(Br)cc(F)cc2[nH]1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 5/20 0.36
GPR17 Q13304 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658782 0.74 DAO (0.42)
SCHEMBL27906754 0.74 DAO (0.44) RHEB
SCHEMBL27697394 0.74 PCSK9 (0.42)
SCHEMBL5777767 0.72 RHEB (0.54) RHEBGPR17
SCHEMBL27551544 0.71 KDM4E (0.36) GPR17
SCHEMBL27473001 0.71 HRH4 (0.38)
SCHEMBL28169311 0.70 CACNA1H (0.39) GPR17
SCHEMBL28118852 0.70
SCHEMBL28952733 0.70 KDM4E (0.31)
SCHEMBL5777310 0.69 CYP2A6 (0.38) GPR17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101535253-A Indole and benzofuran 2-carboxamide derivatives INDOLE AND BENZOFURAN 2 CARBOX (CH) 2009-09-16 CN disclosed