Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 3/20 | 0.36 |
| ▸ | IL2 | P60568 | 3/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491895 | 0.84 | DAO (0.43) | DAODDOMTNR1AMTNR1BFLT3 | |
| SCHEMBL27524233 | 0.84 | DAO (0.43) | DAOMTNR1AMTNR1BFLT3HRH4 | |
| SCHEMBL27965811 | 0.84 | PARP1 (0.40) | MTNR1AMTNR1BHRH4RHEBCTSV | |
| SCHEMBL28678160 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BFLT3HRH4MAPT | |
| SCHEMBL27473001 | 0.82 | HRH4 (0.38) | MTNR1AMTNR1BHRH4MAPTKDM4E | |
| SCHEMBL28291601 | 0.82 | MTNR1A (0.38) | DAODDOMTNR1AMTNR1BRHEB | |
| SCHEMBL27704235 | 0.80 | HRH4 (0.40) | MTNR1AMTNR1BHRH4MAPK1MAPT | |
| SCHEMBL28293158 | 0.80 | MTNR1A (0.39) | MTNR1AMTNR1BRHEBKDM4EALDH1A1 | |
| SCHEMBL27488329 | 0.77 | LOXL2 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL28293162 | 0.77 | JAK2 (0.46) | MTNR1AMTNR1BKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918042-A | 8-methyl-1-phenyl-imidazo [1,5-a ] pyrazine compounds | MSD OSS BV | 2013-02-06 | — | — | CN | disclosed |