SCHEMBL2777845

SCHEMBL2777845

C=Cc1ccc(C(=O)OC(=C)C=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TAS1R3 Q7RTX0 3/20 0.40
TAS1R1 Q7RTX1 3/20 0.40
TDP1 Q9NUW8 1/20 0.36
SNCA P37840 1/20 0.36
KMT2A Q03164 3/20 0.33
MAPT P10636 3/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
GFER P55789 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
RAB9A P51151 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440528 0.85 ALDH1A1 (0.50) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL16520834 0.80 ALDH1A1 (0.41) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL440529 0.78 F2 (0.48) ALDH1A1TDP1KMT2AMAPTRAB9A
SCHEMBL28733839 0.78 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL13482690 0.77 ALDH1A1 (0.50) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL27618266 0.76 TNFRSF1A (0.46) ALDH1A1KMT2AMAPTADRB2ADRB1
SCHEMBL463760 0.76 TDP1 (0.52) ALDH1A1TAS1R3TAS1R1TDP1KMT2A
SCHEMBL16590759 0.75 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL29030380 0.75 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1TDP1SNCA
SCHEMBL24858286 0.73 ALDH1A1 (0.46) ALDH1A1TAS1R3TAS1R1TDP1SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846511-B2 Transparent film and method for manufacturing the same, polarized plate and image display device FUJIFILM CORPORATION (JP) 2010-12-07 US disclosed
US-20080158675-A1 Transparent Film and Method for Manufacturing the Same, Polarized Plate and Image Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
WO-2006077995-A1 TRANSPARENT FILM AND METHOD FOR MANUFACTURING THE SAME, POLARIZED PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-07-27 WO disclosed