SCHEMBL440528

SCHEMBL440528

C=Cc1ccc(C(=O)OC(=O)c2ccc(C=C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 2/20 0.43
TAS1R3 Q7RTX0 3/20 0.42
TAS1R1 Q7RTX1 3/20 0.42
SNCA P37840 1/20 0.41
TSHR P16473 1/20 0.39
PTPN1 P18031 1/20 0.37
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ALDH5A1 P51649 1/20 0.35
ABAT P80404 1/20 0.35
CA12 O43570 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
MAPT P10636 2/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440529 0.92 F2 (0.48) ALDH1A1TDP1TSHRMAPTKMT2A
SCHEMBL27618266 0.90 TNFRSF1A (0.46) ALDH1A1CA1CA2MAPTKMT2A
SCHEMBL463760 0.90 TDP1 (0.52) ALDH1A1TDP1TAS1R3TAS1R1MAPT
SCHEMBL28733839 0.88 ALDH1A1 (0.42) ALDH1A1TDP1TAS1R3TAS1R1SNCA
SCHEMBL13482690 0.86 ALDH1A1 (0.50) ALDH1A1TDP1TAS1R3TAS1R1SNCA
SCHEMBL16520834 0.86 ALDH1A1 (0.41) ALDH1A1TDP1TAS1R3TAS1R1SNCA
SCHEMBL411494 0.86 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1MAPTKMT2A
SCHEMBL2777845 0.85 ALDH1A1 (0.42) ALDH1A1TDP1TAS1R3TAS1R1SNCA
SCHEMBL16590759 0.85 ALDH1A1 (0.39) ALDH1A1TDP1TAS1R3TAS1R1SNCA
SCHEMBL29030380 0.84 ALDH1A1 (0.48) ALDH1A1TDP1TAS1R3TAS1R1SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638928-A Preparation method and application of end-capped modified poly-biphenyl phenolic resin 同宇新材料(广东)股份有限公司 2025-03-18 CN claimed
US-11559777-B2 Microencapsulated polyaddition catalyst CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2023-01-24 US claimed
EP-3592792-B1 MICROENCAPSULATED POLYADDITION CATALYST CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2020-12-16 EP claimed
US-20200385519-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-10 US claimed
CN-111712529-A Method and composition for preparing thermosetting poly (arylene ether) copolymer 沙特基础工业全球技术有限公司 2020-09-25 CN claimed
US-20200038830-A1 Microencapsulated Polyaddition Catalyst SIKA TECHNOLOGY AG (CH) 2020-02-06 US claimed
EP-3571241-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SABIC Global Technologies B.V. (NL) 2019-11-27 EP claimed
WO-2019116309-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-20 WO claimed
US-8507659-B2 Method for chemically modifying biopolymer and polypeptide FUJIFILM CORPORATION (JP) 2013-08-13 US claimed
US-8399539-B2 Soluble silicone prepolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-03-19 US claimed
US-20120065348-A1 SOLUBLE SILICONE PREPOLYMERS TORAY INDUSTRIES, INC. (JP) 2012-03-15 US claimed
US-8080622-B2 Soluble silicone prepolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-12-20 US claimed
EP-2164882-A1 SOLUBLE SILICONE PREPOLYMERS Johson & Johnson Vision Care Inc. (US) 2010-03-24 EP claimed
WO-2009006285-A1 SOLUBLE SILICONE PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2009-01-08 WO claimed
US-20090005528-A1 SOLUBLE SILICONE PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. 2009-01-01 US claimed
US-5596051-A Microcapsules, the production and use thereof BASF AKTIENGESELLSCHAFT (DE) 1997-01-21 US claimed
CN-113264918-B Coloring composition, compound, color filter and display device 住友化学株式会社 2025-04-22 CN disclosed
CN-119816544-A Composition, cured product, display device, and solid-state imaging device 住友化学株式会社 2025-04-11 CN disclosed
US-5596051-A Microcapsules, the production and use thereof BASF AKTIENGESELLSCHAFT (DE) 1997-01-21 US disclosed
US-5596051-A Microcapsules, the production and use thereof BASF AKTIENGESELLSCHAFT (DE) 1997-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005528-A1 SOLUBLE SILICONE PREPOLYMERS NOS3, NOS2, PCNA ALDH1A1 2292/4885TDP1 948/4885TAS1R3 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.