SCHEMBL27779481

SCHEMBL27779481

Clc1cc(Cl)c(Cl)c(C(Cl)(Cl)Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
TSHR P16473 9/20 0.43
HPGD P15428 7/20 0.43
HSD17B10 Q99714 7/20 0.43
CASP1 P29466 1/20 0.43
AHR P35869 8/20 0.42
MAPK1 P28482 4/20 0.40
ALDH1A1 P00352 2/20 0.40
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CYP1B1 Q16678 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
HSP90AA1 P07900 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
EGFR P00533 1/20 0.33
LMNA P02545 1/20 0.33
ESR1 P03372 1/20 0.33
ERBB2 P04626 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601275 0.84 TSHR (0.44) CYP3A4TSHRHPGDHSD17B10CASP1
SCHEMBL3388256 0.75 TSHR (0.32) TSHR
SCHEMBL31424062 0.75 TSHR (0.32) TSHR
SCHEMBL10493668 0.73 CYP3A4 (0.35) CYP3A4TSHRMAPK1TDP1CYP2C19
SCHEMBL14131044 0.73 CYP3A4 (0.47) CYP3A4TSHRHPGDHSD17B10CASP1
SCHEMBL16103006 0.73 CYP3A4 (0.47) CYP3A4TSHRHPGDHSD17B10CASP1
SCHEMBL28645554 0.73 TSHR (0.40) CYP3A4TSHRAHRMAPK1TDP1
SCHEMBL1538519 0.72 TSHR (0.30) TSHR
SCHEMBL348913 0.71 AHR (0.67) CYP3A4TSHRHPGDHSD17B10CASP1
Pentachlorobenzene SCHEMBL2139718 0.69 CYP3A4 (0.85) CYP3A4TSHRHPGDHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406339-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2021-10-26 CN disclosed
CN-109020773-B Method for synthesizing alpha-olefin by ethylene oligomerization and pretreatment method of catalyst and solvent thereof 中国石油天然气股份有限公司 2021-08-03 CN disclosed
CN-107074679-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2020-11-17 CN disclosed
CN-107406345-B Process for producing alpha-olefin oligomer 三菱化学株式会社 2020-08-11 CN disclosed
CN-107406339-A Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2017-11-28 CN disclosed
CN-107406345-A Process for producing alpha-olefin oligomer 三菱化学株式会社 2017-11-28 CN disclosed
CN-101547944-B Process for producing polyolefin, and 1-hexene for raw material for producing linear low density polyethylene MITSUBISHI CHEM CORP 2013-07-24 CN disclosed
CN-101547941-B Process for producing alpha-olefin oligomer MITSUBISHI CHEMICAL CORP. (JP) 2011-12-28 CN disclosed
CN-101553450-A Process for producing ethylene oligomer MITSUBISHI CHEM CORP (JP) 2009-10-07 CN disclosed
CN-101547941-A Process for producing alpha-olefin oligomer MITSUBISHI CHEM CORP (JP) 2009-09-30 CN disclosed
CN-101547944-A Process for producing polyolefin, and 1-hexene for raw material for producing linear low density polyethylene MITSUBISHI CHEM CORP (JP) 2009-09-30 CN disclosed