SCHEMBL348913

SCHEMBL348913

Clc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.67
MAPK1 P28482 2/20 0.67
CYP3A4 P08684 2/20 0.58
TSHR P16473 6/20 0.57
HSD17B10 Q99714 5/20 0.57
HPGD P15428 4/20 0.57
FLT1 P17948 1/20 0.50
CASP1 P29466 1/20 0.47
TP53 P04637 1/20 0.47
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MAPK13 O15264 1/20 0.41
CDK1 P06493 1/20 0.41
PIM1 P11309 1/20 0.41
DYRK1A Q13627 1/20 0.41
PIM3 Q86V86 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
GRIN2D O15399 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 0.82 AHR (1.00) AHRMAPK1CYP3A4TSHRHSD17B10
2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 0.82 AHR (1.00) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL13197717 0.78 AHR (0.53) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL5792991 0.78 AHR (0.47) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL7594519 0.76 AHR (0.44) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL10872182 0.76 AHR (0.57) AHRMAPK1CYP3A4TSHRHSD17B10
Triclofenol SCHEMBL1338 0.76 HSD17B10 (1.00) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL7940907 0.76 AHR (0.44) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL1436824 0.76 AHR (0.44) AHRMAPK1CYP3A4TSHRHSD17B10
SCHEMBL9760840 0.76 AHR (0.44) AHRMAPK1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414462-B2 Organic single crystal composite oriented polymer membrane, preparation method therefor, optoelectronic device and application thereof ZHEJIANG UNIVERSITY (CN) 2025-09-09 US claimed
CN-120057904-A Halogen and nitrogen element co-doped graphene composite material loading metal active site, hydrogen evolution electrode, preparation method and application 上海交通大学 2025-05-30 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
US-20250120305-A1 ORGANIC SINGLE CRYSTAL COMPOSITE ORIENTED POLYMER MEMBRANE, PREPARATION METHOD THEREFOR, OPTOELECTRONIC DEVICE AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2025-04-10 US claimed
US-12258448-B2 Method of making a biphenol dianhydride composition, method for purification of a biphenol dianhydride composition, and poly (etherimides) derived from the biphenol dianhydride SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-03-25 US claimed
CN-119633844-A Selective hydrogenation dechlorination catalyst for chlorinated organic compounds and preparation method thereof 江苏扬农化工集团有限公司 2025-03-18 CN claimed
CN-119565645-A Continuous hydrogenation dechlorination catalyst and preparation method thereof 江苏扬农化工集团有限公司 2025-03-07 CN claimed
CN-119368019-A Acid and alkali resistant composite filter membrane and preparation method and application thereof 苏州仿生材料科学与工程中心 2025-01-28 CN claimed
CN-114002351-B Gas chromatography-mass spectrometry detection method for simultaneously detecting tetrachlorobenzene and pentachlorobenzene in chlorothalonil 江苏新河农用化工有限公司 2024-12-13 CN claimed
WO-2024187552-A1 THIN FILM COMPOSITING ORGANIC SINGLE CRYSTAL AND ORIENTED POLYMER, PREPARATION METHOD, AND PHOTOELECTRIC DEVICE AND USE 浙江大学 2024-09-19 WO claimed
EP-0301343-A1 Process for the preparation of 1,2-dichlorobenzene BAYER AG (DE) 1989-02-01 EP claimed
US-4673465-A Separation of m-xylene from o-xylene by extractive distillation with polychloro compounds BERG LLOYD 1987-06-16 US claimed
US-4629815-A ALKALI METAL AMIDE OR ALKALI METAL ALCOHOLATE AND COMPLEXING AGENT RHONE-POULENC INDUSTRIES (FR) 1986-12-16 US claimed
EP-0044366-B1 DISTILLATIVE FREEZING PROCESS FOR SEPARATING CLOSE BOILING MIXTURES Cheng, Chen-Yen (US) 1985-01-09 EP claimed
EP-0043303-B1 PROCESS FOR THE ISOMERIZATION AND/OR REARRANGEMENT OF POLYCHLOROBENZENES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-09-21 EP claimed
US-4299668-A USING PENTACHLOROPHENOL MIXED WITH CERTAIN CHLORINATED AND/OR OXYGENATED COMPOUNDS INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) 1981-11-10 US claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4205014-A LEWIS ACID AND AN IODINATED RESIN AS COCATALYSIS THE DOW CHEMICAL COMPANY (US) 1980-05-27 US claimed
US-4186153-A Process for 1,2,4,5-tetrachlorobenzene THE DOW CHEMICAL COMPANY (US) 1980-01-29 US claimed
US-3972820-A HALOGENATED COMPOUND, OXIDIZER, BINDER FUEL THE DOW CHEMICAL COMPANY (US) 1976-08-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258448-B2 Method of making a biphenol dianhydride composition, method for purification of a biphenol dianhydride composition, and poly (etherimides) derived from the biphenol dianhydride CA3, FHIT, PPIP5K2 AHR 532/4885MAPK1 2356/4885CYP3A4 1894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.