Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965851 | 0.93 | POLB (0.63) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28584149 | 0.93 | POLB (0.68) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28190202 | 0.82 | KMT2A (0.52) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL15092194 | 0.81 | POLB (0.84) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28591383 | 0.81 | ELANE (0.71) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL23291730 | 0.79 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL13292719 | 0.79 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28619993 | 0.79 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6689211 | 0.79 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL17287375 | 0.79 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-115073421-B | Carboxylic aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115137726-A | Carboxylic acid aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115068468-A | Carboxylic aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073421-A | Carboxylic acid aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-110325523-B | Carboxylic acid aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-101528740-B | Heteroaryl-pyrazole derivatives as cannabinoid CB1 receptor antagonists | GREEN CROSS CORP | 2012-09-19 | — | — | CN | disclosed |
| CN-101646652-A | Quinoline derivatives and pharmaceutical compositions comprising them for selectin inhibition | WYETH CORP US | 2010-02-10 | — | — | CN | disclosed |
| CN-101528740-A | Heteroaryl-pyrazole derivatives as cannabinoid CB1 receptor antagonists | GREEN CROSS CORP (KR) | 2009-09-09 | — | — | CN | disclosed |