Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585415 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL10483701 | 0.84 | ELANE (1.00) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL28596195 | 0.83 | ELANE (0.71) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL28590426 | 0.83 | ELANE (0.71) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL28588041 | 0.83 | ELANE (0.66) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL28588045 | 0.82 | ELANE (0.69) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL27779967 | 0.81 | POLB (0.58) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL28581291 | 0.80 | ELANE (0.66) | ELANEPOLBKMT2AHTTTDP1 | |
| SCHEMBL3677325 | 0.79 | SRD5A2 (0.53) | POLBTDP1L3MBTL1PARP1 | |
| SCHEMBL3445668 | 0.78 | PARP1 (0.63) | TDP1L3MBTL1ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |