Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084385 | 0.93 | TSHR (0.52) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| SCHEMBL2778 | 0.93 | TSHR (0.52) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| SCHEMBL6383298 | 0.91 | TSHR (0.50) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| Acetone SCHEMBL29281281 | 0.91 | TSHR (0.50) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| SCHEMBL1896602 | 0.91 | TSHR (0.50) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| Acetic Acid SCHEMBL28536661 | 0.89 | TSHR (0.48) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| SCHEMBL154741 | 0.85 | ALDH1A1 (0.58) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| Phosphoric Acid SCHEMBL28487093 | 0.85 | TSHR (0.46) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| SCHEMBL18688239 | 0.83 | TSHR (0.44) | TSHRITGB1ITGA5ALDH1A1LMNA | |
| Acetic Acid SCHEMBL28815277 | 0.83 | ALDH1A1 (0.56) | TSHRITGB1ITGA5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291181-A1 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | WYETH (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | BACE1, BACE2, APP | TSHR 4663/4885ITGB1 2336/4885ITGA5 3715/4885 |
| US-20100291181-A1 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH | MMP1, FGF2, FGF1 | TSHR 4012/4885ITGB1 786/4885ITGA5 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.