SCHEMBL2778023

SCHEMBL2778023

C1COC(C2CCC(C3=NCCO3)CC2)=N1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 4/20 0.38
ADRA2B P18089 4/20 0.38
ADRA2C P18825 4/20 0.38
ADRA1A P35348 3/20 0.38
GMNN O75496 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1A P08908 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
OPRK1 P41145 1/20 0.38
HIF1A Q16665 1/20 0.38
NISCH Q9Y2I1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612832 1.00
SCHEMBL11740603 0.90
SCHEMBL961726 0.90 ADRA2A (0.44) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL961378 0.88 ADRA2A (0.47) ADRA2AADRA2BADRA2CADRA1AGMNN
Hydrogen Sulfide SCHEMBL721911 0.86 ADRA2A (0.46) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL9322130 0.85 NOS3 (0.44) ADRA2AADRA2BADRA2CADRA1ANISCH
SCHEMBL2782843 0.81 ADRA2A (0.37) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL11743173 0.79 ADRA2A (0.38) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL21443560 0.77
SCHEMBL25209847 0.77 NOS3 (0.41) ADRA2AADRA2BADRA2CADRA1ANISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666834-B1 INK-JET INK COMPOSITION FOR TEXTILE PRINTING SAKATA INX CORP (JP) 2025-06-25 EP disclosed
WO-2025074466-A1 CONVEYING MEMBER 早川ゴム株式会社 2025-04-10 WO disclosed
CN-114058379-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal element JSR株式会社 2024-12-27 CN disclosed
CN-113025346-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal element JSR株式会社 2024-11-29 CN disclosed
CN-114761866-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and method for manufacturing liquid crystal display element 日产化学株式会社 2024-07-30 CN disclosed
CN-118056157-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-17 CN disclosed
EP-3296327-B1 METHOD FOR PRODUCING ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS INC (JP) 2024-05-15 EP disclosed
CN-113573906-B Surface treating agent and article DIC株式会社 2023-11-17 CN disclosed
CN-110093167-B Liquid crystal aligning agent, liquid crystal alignment film, method for producing liquid crystal alignment film, and liquid crystal element JSR株式会社 2023-09-19 CN disclosed
CN-111542779-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal element JSR株式会社 2023-08-22 CN disclosed
EP-0266708-B1 CROSS-LINKED RESINS AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1991-07-03 EP disclosed
US-4945137-A Binder combinations and a process for the production of flat materials BAYER AKTIENGESELLSCHAFT (DE) 1990-07-31 US disclosed
US-4931512-A REACTING POLY(CYCLIC IMINOETHER) WITH POLYOLS OR POLYAMINES, ACID CATALYST; CURABLE TEIJIN LIMITED (JP) 1990-06-05 US disclosed
EP-0363757-A2 Coupling agent compositions and process for the manufacture of flat materials BAYER AG (DE) 1990-04-18 EP disclosed
US-4910265-A Poly(cyclic iminoether) and an acid catalyst TEIJIN LIMITED (JP) 1990-03-20 US disclosed
EP-0336390-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1989-10-11 EP disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed
US-4837302-A STRENGTH AND HEAT RESISTANCE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-06-06 US disclosed
EP-0273368-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1988-07-06 EP disclosed
EP-0266708-A1 Cross-linked resins and production thereof TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1988-05-11 EP disclosed