Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11161811 | 0.85 | GPR84 (0.45) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL11166753 | 0.85 | GPR84 (0.45) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL28727677 | 0.83 | GPR84 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL28727393 | 0.83 | GPR84 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL28729115 | 0.83 | GPR84 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL28727659 | 0.83 | GPR84 (0.44) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL11160056 | 0.83 | CA2 (0.43) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL8490437 | 0.82 | GPR84 (0.42) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL20954009 | 0.81 | CA2 (0.42) | GPR84FFAR1PPARDMAPTLCK | |
| SCHEMBL7873967 | 0.79 | GPR84 (0.44) | GPR84FFAR1PPARDMAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555205-B | Preparing method of 3-oxo-1-cyclobutane-carboxylic acid | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2011-11-23 | — | — | CN | disclosed |
| CN-101555205-A | Preparing method of 3-oxo-1-cyclobutane-carboxylic acid | ZHEJIANG GENEBEST PHARMACEUTIC (CN) | 2009-10-14 | — | — | CN | disclosed |