Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896947 | 0.83 | NPC1 (0.46) | NPC1RAB9AKMT2APOLBATM | |
| SCHEMBL28435056 | 0.82 | HTR1A (0.42) | NPC1RAB9AKMT2AATML3MBTL1 | |
| SCHEMBL30811376 | 0.82 | KMT2A (0.41) | NPC1RAB9AKMT2AL3MBTL1GLA | |
| SCHEMBL11836426 | 0.78 | KMT2A (0.47) | NPC1RAB9AKMT2ATDP1GLA | |
| SCHEMBL28436994 | 0.75 | TAAR1 (0.41) | NPC1RAB9AKMT2APOLBGLA | |
| SCHEMBL2976001 | 0.75 | NPC1 (0.59) | NPC1RAB9AKMT2APOLBATM | |
| SCHEMBL18631772 | 0.74 | NPC1 (0.46) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL7950844 | 0.73 | KMT2A (0.51) | NPC1RAB9AKMT2ARXRARXRB | |
| SCHEMBL3711831 | 0.73 | POLB (0.54) | NPC1RAB9AKMT2APOLBL3MBTL1 | |
| SCHEMBL28358852 | 0.73 | KMT2A (0.67) | NPC1RAB9AKMT2AL3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094375-B | Blocking agent dissociation catalyst for blocked isocyanate and thermosetting composition containing the same | 广荣化学株式会社 | 2022-04-01 | — | — | CN | disclosed |
| CN-111094375-A | Blocking agent dissociation catalyst for blocked isocyanate and thermosetting composition containing the same | 广荣化学工业株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-101665565-B | Method for preparing polylactic acid by catalysis of carbene derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2012-01-04 | — | — | CN | disclosed |
| CN-101665565-A | Method for preparing polylactic acid by catalysis of carbene derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2010-03-10 | — | — | CN | disclosed |