Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18631772 | 0.84 | NPC1 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27780684 | 0.83 | NPC1 (0.45) | NPC1RAB9AKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL28431158 | 0.81 | TAAR1 (0.44) | NPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL28727289 | 0.78 | LMNA (0.51) | NPC1RAB9AKMT2AALDH1A1HSD17B10 | |
| SCHEMBL30811376 | 0.78 | KMT2A (0.41) | NPC1RAB9AKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2976001 | 0.76 | NPC1 (0.59) | NPC1RAB9AKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11836426 | 0.76 | KMT2A (0.47) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL727155 | 0.73 | NPC1 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL262815 | 0.72 | — | — | |
| SCHEMBL19476143 | 0.72 | NPC1 (0.47) | NPC1RAB9AKMT2ATAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094375-B | Blocking agent dissociation catalyst for blocked isocyanate and thermosetting composition containing the same | 广荣化学株式会社 | 2022-04-01 | — | — | CN | disclosed |
| CN-111094375-A | Blocking agent dissociation catalyst for blocked isocyanate and thermosetting composition containing the same | 广荣化学工业株式会社 | 2020-05-01 | — | — | CN | disclosed |