Nitrogen

Nitrogen

SCHEMBL27780715

N#N.NC(=O)c1ccc(Cl)cc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 6/20 0.58
CES2 O00748 2/20 0.56
CES1 P23141 2/20 0.56
TSHR P16473 2/20 0.54
ALOX15 P16050 1/20 0.54
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
PARP1 P09874 2/20 0.50
KMT2A Q03164 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
PARP4 Q9UKK3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959902 0.95 MAP4K4 (0.62) MAP4K4CES2CES1TSHRALOX15
SCHEMBL77931 0.95 MAP4K4 (0.62) MAP4K4CES2CES1TSHRALOX15
Hydrochloric Acid SCHEMBL409480 0.92 MAP4K4 (0.60) MAP4K4CES2CES1TSHRALOX15
Bromide SCHEMBL28799121 0.92 MAP4K4 (0.60) MAP4K4CES2CES1TSHRALOX15
Iodide SCHEMBL19056893 0.92 MAP4K4 (0.60) MAP4K4CES2CES1TSHRALOX15
Hydrochloric Acid SCHEMBL3772040 0.92 MAP4K4 (0.60) MAP4K4CES2CES1TSHRALOX15
Hydrochloric Acid SCHEMBL28021646 0.92 MAP4K4 (0.60) MAP4K4CES2CES1TSHRALOX15
SCHEMBL2689662 0.88 MAP4K4 (0.72) MAP4K4CES2CES1TSHRALOX15
Benzamide SCHEMBL9812910 0.86 PARP1 (0.73) MAP4K4CES2CES1TSHRALOX15
4-Chloroaniline SCHEMBL11600778 0.86 PARP10 (0.61) MAP4K4CES2CES1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103848752-A Novel synthesis process of P-chlorophenylhydrazine hydrochloride UNIV NANJING SCIENCE & TECH 2014-06-11 CN claimed
CN-102285900-B Method for preparing 3-(2,6-dichlorophenyl)-2,3-dioxy ethyl propionate-2-(4-chlorphenyl) hydrazone SHANGHAI HETENG FINE CHEMICAL CO LTD 2013-10-02 CN claimed
CN-102285900-A Method for preparing 3-(2,6-dichlorophenyl)-2,3-dioxy ethyl propionate-2-(4-chlorphenyl) hydrazone 2011-12-21 CN claimed
CN-101555249-A Method for synthesizing famciclovir ZHEJIANG HISUN PHARMACEUTICAL (CN) 2009-10-14 CN claimed
CN-103848752-A Novel synthesis process of P-chlorophenylhydrazine hydrochloride UNIV NANJING SCIENCE & TECH 2014-06-11 CN disclosed
CN-102285900-B Method for preparing 3-(2,6-dichlorophenyl)-2,3-dioxy ethyl propionate-2-(4-chlorphenyl) hydrazone SHANGHAI HETENG FINE CHEMICAL CO LTD 2013-10-02 CN disclosed
CN-103265511-A Synthetic method of A-803467 key intermediate UNIV ZHENGZHOU 2013-08-28 CN disclosed
CN-102344587-B Modified rubber containing carbon nano tube and preparation method thereof PETROCHINA CO LTD 2013-07-31 CN disclosed
CN-102603683-A Furan compound and preparation method and application of furan compound UNIV SHANDONG 2012-07-25 CN disclosed
CN-102344587-A Modified rubber containing carbon nano tube and preparation method thereof PETROCHINA CO LTD 2012-02-08 CN disclosed
CN-102285900-A Method for preparing 3-(2,6-dichlorophenyl)-2,3-dioxy ethyl propionate-2-(4-chlorphenyl) hydrazone 2011-12-21 CN disclosed
CN-102206190-A High-efficient antimicrobial triazole compound and preparation method thereof UNIV TIANJIN TECHNOLOGY 2011-10-05 CN disclosed
CN-102199128-A High-efficiency antibacterial triazole compound and preparation method thereof UNIV TIANJIN TECHNOLOGY 2011-09-28 CN disclosed
CN-101555249-B Method for synthesizing famciclovir ZHEJIANG HISUN PHARM CO LTD 2011-05-11 CN disclosed
CN-101555249-A Method for synthesizing famciclovir ZHEJIANG HISUN PHARMACEUTICAL (CN) 2009-10-14 CN disclosed