Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 6/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780999 | 0.83 | KDM4E (0.43) | KIF11KDM4EMAPTSLC6A4HTR1A | |
| SCHEMBL734743 | 0.79 | OPRM1 (0.50) | MEN1KMT2AKIF11 | |
| SCHEMBL27780918 | 0.78 | AHR (0.43) | MEN1KMT2AKDM4EMAPTSLC6A4 | |
| SCHEMBL733091 | 0.78 | MEN1 (0.40) | MEN1KMT2AKIF11KDM4ECNR1 | |
| SCHEMBL733092 | 0.78 | MEN1 (0.40) | MEN1KMT2AKIF11KDM4ECNR1 | |
| SCHEMBL734186 | 0.77 | OPRM1 (0.43) | MEN1KMT2AKIF11CNR1 | |
| Hydrochloric Acid SCHEMBL27825988 | 0.77 | AHR (0.42) | MEN1KMT2AKDM4EMAPTSLC6A4 | |
| SCHEMBL10067373 | 0.74 | KIF11 (0.46) | MEN1KMT2AKIF11CNR1HTR1B | |
| SCHEMBL29956270 | 0.72 | KDM4E (0.44) | MEN1KMT2AKIF11KDM4ECNR1 | |
| SCHEMBL16729570 | 0.71 | MEN1 (0.64) | MEN1KMT2AKIF11KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516844-B | 4-heteroaryl substituted 1-aminocyclohexane-1-and cyclohexene-1-derivatives having activity on opioid receptor systems | GRUENENTHAL GMBH | 2013-12-11 | — | — | CN | claimed |
| CN-101516844-A | 4-heteroaryl substituted 1-aminocyclohexane-1-and cyclohexene-1-derivatives having activity on opioid receptor systems | GRUENENTHAL GMBH (DE) | 2009-08-26 | — | — | CN | claimed |
| CN-101516844-B | 4-heteroaryl substituted 1-aminocyclohexane-1-and cyclohexene-1-derivatives having activity on opioid receptor systems | GRUENENTHAL GMBH | 2013-12-11 | — | — | CN | disclosed |
| CN-101516844-A | 4-heteroaryl substituted 1-aminocyclohexane-1-and cyclohexene-1-derivatives having activity on opioid receptor systems | GRUENENTHAL GMBH (DE) | 2009-08-26 | — | — | CN | disclosed |