Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944811 | 0.99 | RAB9A (0.51) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28784003 | 0.95 | RAB9A (0.52) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29291197 | 0.87 | RAB9A (0.51) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27782459 | 0.86 | KDM4E (0.50) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5685113 | 0.85 | CDK1 (0.59) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27804108 | 0.85 | CDK1 (0.49) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4045458 | 0.85 | RAB9A (0.59) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27804111 | 0.82 | RAB9A (0.51) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2455047 | 0.79 | KDM4E (0.53) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31501839 | 0.78 | KDM4E (0.61) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101743224-A | 7-substituted indole mcl-1 inhibitors | ABBOTT LAB | 2010-06-16 | — | — | CN | disclosed |