Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218450 | 0.87 | PRKAB2 (0.52) | TSHRSRD5A2FOLH1MAPK14EPHX2 | |
| SCHEMBL3217027 | 0.86 | PRKAB2 (0.51) | TSHRSRD5A2FOLH1MAPK14EPHX2 | |
| SCHEMBL6254017 | 0.85 | TSHR (0.61) | TSHRSRD5A2MAPK14ALDH1A1MAPT | |
| SCHEMBL3222396 | 0.84 | TSHR (0.49) | TSHRSRD5A2FOLH1MAPK14EPHX2 | |
| SCHEMBL3210729 | 0.83 | TSHR (0.47) | TSHRSRD5A2FOLH1MAPK14EPHX2 | |
| SCHEMBL27760928 | 0.81 | GRIK1 (0.52) | FOLH1MAPK14RXRARXRBRARB | |
| SCHEMBL27760876 | 0.81 | RARB (0.49) | FOLH1MAPK14ALDH1A1MAPTRXRA | |
| SCHEMBL3220302 | 0.81 | TSHR (0.45) | TSHRSRD5A2FOLH1RARBSMN1; SMN2 | |
| SCHEMBL3220340 | 0.80 | TSHR (0.55) | TSHRSRD5A2ALDH1A1MAPTRXRA | |
| SCHEMBL3207912 | 0.80 | TSHR (0.55) | TSHRSRD5A2MAPK14ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506155-A | Biphenyl derivatives and their use in the treatment of hepatitis C | ARROW THERAPEUTICS LTD (GB) | 2009-08-12 | — | — | CN | disclosed |