Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27760928 | 0.81 | GRIK1 (0.52) | RARBFOLH1MAPK14RXRARXRB | |
| SCHEMBL27782559 | 0.81 | TSHR (0.49) | RARBFOLH1MAPK14PRKAB2PRKAG1 | |
| SCHEMBL16554362 | 0.80 | TSHR (0.55) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL3215926 | 0.80 | KMO (0.52) | PTGER1KDM4ELMNAHSD17B10BCL2L1 | |
| SCHEMBL16554472 | 0.80 | PTGER1 (0.52) | PTGER1KDM4ETTRALDH1A1KMT2A | |
| SCHEMBL2555397 | 0.79 | MAPT (0.48) | RARBPTGER1MAPK14KDM4ELMNA | |
| SCHEMBL2560576 | 0.76 | ALDH1A1 (0.56) | RARBPTGER1MAPK14KDM4ELMNA | |
| SCHEMBL129853 | 0.75 | ALDH1A1 (0.60) | RARBKDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2744832 | 0.75 | SLC22A12 (0.56) | RARBKDM4ELMNAHSD17B10 | |
| SCHEMBL31038313 | 0.75 | CA1 (0.58) | KDM4ELMNAPRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506155-A | Biphenyl derivatives and their use in the treatment of hepatitis C | ARROW THERAPEUTICS LTD (GB) | 2009-08-12 | — | — | CN | disclosed |