Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611220 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL6447670 | 0.78 | CA1 (0.50) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL911096 | 0.77 | CA1 (0.48) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL8943724 | 0.75 | CA1 (0.47) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL9318733 | 0.75 | CA1 (0.58) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL2277677 | 0.75 | CA1 (0.58) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL27728856 | 0.75 | CYP1A2 (0.53) | ALDH1A1CYP1A2CYP2D6CYP2C19MIF | |
| SCHEMBL11515799 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL365643 | 0.73 | TDP1 (0.56) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL8504322 | 0.72 | MIF (0.49) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555211-B | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101555211-A | Chemical synthesis method of 2-acylamino-3-biphenyl propionic acid | ZHEJIANG JIUZHOU PHARMACEUTICA (CN) | 2009-10-14 | — | — | CN | disclosed |