Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716539 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAALMNACYP1A2CYP2D6 | |
| SCHEMBL27782838 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GAATSHRMAPK1TDP1 | |
| SCHEMBL5176160 | 0.78 | ALDH1A1 (0.56) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL5054937 | 0.78 | ALDH1A1 (0.60) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL8747263 | 0.77 | AOC3 (0.44) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| SCHEMBL956691 | 0.77 | ALDH1A1 (0.55) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL8010946 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAALMNATDP1CA1 | |
| SCHEMBL9185138 | 0.75 | TSHR (0.54) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL1200448 | 0.75 | TSHR (0.54) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL3960014 | 0.75 | TRPA1 (0.54) | ALDH1A1GAALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249447-B1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | ALEMBIC LTD (IN) | 2008-10-22 | — | — | EP | claimed |
| US-6756502-B2 | AS CHEMICAL INTERMEDIATE IN PREPARATION OF VENLAFAXINE | ALEMBIC LIMITED (IN) | 2004-06-29 | — | — | US | claimed |
| US-20030195376-A1 | Novel intermediate and processes for its preparation and conversion into a pharmacologically-active agent | ALEMBIC LIMITED (A CORPORATION OF INDIA) (IN) | 2003-10-16 | — | — | US | claimed |
| EP-1249447-A1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | Alembic Limited (IN) | 2002-10-16 | — | — | EP | claimed |
| EP-1249447-B1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | ALEMBIC LTD (IN) | 2008-10-22 | — | — | EP | disclosed |
| EP-1249447-B1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | ALEMBIC LTD (IN) | 2008-10-22 | — | — | EP | disclosed |
| US-20070027156-A1 | Crf antagonists and heterobicyclic compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| CN-1878758-A | Crf antagonists and heterobicyclic compounds | ONO PHARMACEUTICAL CO (JP) | 2006-12-13 | — | — | CN | disclosed |
| EP-1666468-A1 | CRF ANTAGONISTS AND HETEROBICYCLIC COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-6756502-B2 | AS CHEMICAL INTERMEDIATE IN PREPARATION OF VENLAFAXINE | ALEMBIC LIMITED (IN) | 2004-06-29 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-20030195376-A1 | Novel intermediate and processes for its preparation and conversion into a pharmacologically-active agent | ALEMBIC LIMITED (A CORPORATION OF INDIA) (IN) | 2003-10-16 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| EP-1249447-A1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | Alembic Limited (IN) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195376-A1 | Novel intermediate and processes for its preparation and conversion into a pharmacologically-active agent | CYP3A4, CYP4X1, CYP2F1 | ALDH1A1 526/4885GAA 1692/4885LMNA 1089/4885 |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | ALDH1A1 792/4885GAA 1674/4885LMNA 2427/4885 |
| US-20070027156-A1 | Crf antagonists and heterobicyclic compounds | CRHR2, CRHR1, CRH | ALDH1A1 3380/4885GAA 4725/4885LMNA 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.