Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 4/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762656 | 0.87 | CASP3 (0.39) | ALDH1A1CASP3CASP8CASP1CASP7 | |
| SCHEMBL27784520 | 0.85 | KDM4E (0.39) | ALDH1A1CASP3CASP8CASP1CASP7 | |
| SCHEMBL27784534 | 0.82 | KDM4E (0.40) | ALDH1A1CASP3CASP8CASP1CASP7 | |
| SCHEMBL1306543 | 0.82 | HDAC3 (0.42) | ALDH1A1KMT2ACASP3HDAC3HDAC1 | |
| SCHEMBL29488463 | 0.82 | HDAC3 (0.42) | ALDH1A1KMT2ACASP3HDAC3HDAC1 | |
| SCHEMBL1306548 | 0.82 | HDAC3 (0.42) | ALDH1A1KMT2ACASP3HDAC3HDAC1 | |
| SCHEMBL1306701 | 0.81 | HDAC1 (0.49) | ADAMTS4ADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL1306703 | 0.81 | HDAC1 (0.49) | ADAMTS4ADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL29488482 | 0.81 | HDAC1 (0.49) | ADAMTS4ADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL1305816 | 0.79 | ALDH1A1 (0.37) | ADAMTS4ADAMTS5ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573327-A | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RES INST CHEM TECH (KR) | 2009-11-04 | — | — | CN | disclosed |