Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703276 | 0.85 | KDM4E (0.65) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7825295 | 0.85 | KDM4E (0.65) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14970288 | 0.73 | KDM4E (0.73) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209362 | 0.73 | KDM4E (0.73) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11236067 | 0.73 | KDM4E (0.54) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7830543 | 0.73 | KDM4E (1.00) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14970274 | 0.69 | KDM4E (0.56) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209378 | 0.69 | KDM4E (0.56) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209979 | 0.69 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209975 | 0.69 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101775021-A | Method for selective synthesis of alpha-narcotine with participation of blockage group | UNIV SHENYANG PHARMACEUTICAL | 2010-07-14 | — | — | CN | claimed |