Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793999 | 0.75 | FAAH (0.40) | DDB1CRBNCYP3A4CYP2D6 | |
| SCHEMBL28201013 | 0.73 | HSD17B3 (0.42) | MAOBDDB1CRBNGBA1 | |
| SCHEMBL3194253 | 0.71 | GBA1 (0.46) | DDB1CRBNGBA1SLC6A2SLC6A4 | |
| SCHEMBL694287 | 0.71 | MAOB (0.48) | MAOBGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11025374 | 0.71 | GBA1 (0.46) | DDB1CRBNGBA1SLC6A2SLC6A4 | |
| SCHEMBL11025378 | 0.71 | GBA1 (0.46) | DDB1CRBNGBA1SLC6A2SLC6A4 | |
| SCHEMBL27348898 | 0.71 | SLC6A2 (0.46) | DDB1CRBNSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9854900 | 0.70 | GBA1 (0.44) | DDB1CRBNGBA1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9854904 | 0.70 | GBA1 (0.44) | DDB1CRBNGBA1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9855019 | 0.70 | GBA1 (0.44) | DDB1CRBNGBA1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573357-B | Indole compound | TAKAEDA CHEMICAL IND LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101573357-A | Indole compound | TAKEDA PHARMACEUTICAL (JP) | 2009-11-04 | — | — | CN | disclosed |