Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784635 | 0.73 | MAOB (0.45) | DDB1CRBNMAOBGBA1 | |
| SCHEMBL30425227 | 0.73 | ALDH1A1 (0.45) | HSD17B3MAPTTDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL228875 | 0.73 | POLB (0.44) | FAAHPOLBGBA1 | |
| SCHEMBL30612952 | 0.67 | — | — | |
| SCHEMBL28793999 | 0.67 | FAAH (0.40) | DDB1CRBNFAAHSMN1; SMN2POLB | |
| SCHEMBL4655299 | 0.66 | MAPT (0.66) | MAPTTDP1SMN1; SMN2GBA1CYP1A2 | |
| SCHEMBL3127110 | 0.66 | GBA1 (0.53) | DDB1CRBNGBA1 | |
| SCHEMBL15270681 | 0.65 | KMT2A (0.50) | DDB1CRBNMAOBPOLB | |
| SCHEMBL8906209 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL18428940 | 0.64 | GBA1 (0.52) | DDB1CRBNGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739349-A | The synthetic method of the thioketones of 3 benzyl, 1,3 thiazole 2 and application | 山东京博石油化工有限公司 | 2018-02-27 | — | — | CN | disclosed |