Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27778363 | 0.82 | BCHE (0.40) | BCHEPDPK1RENBACE1AHR | |
| Ethoxycarbonyl Group SCHEMBL28003566 | 0.82 | AHR (0.62) | BCHEPDPK1RENBACE1AHR | |
| Ethoxycarbonyl Group SCHEMBL27784759 | 0.80 | REN (0.32) | RENKMT2A | |
| SCHEMBL29467533 | 0.79 | AHR (0.56) | JAK2RPS6KA3MELKSTK24BCHE | |
| SCHEMBL398827 | 0.79 | AHR (0.56) | JAK2RPS6KA3MELKSTK24BCHE | |
| Ethoxycarbonyl Group SCHEMBL27762816 | 0.78 | AHR (0.37) | BCHERENAHR | |
| Ethoxycarbonyl Group SCHEMBL27476172 | 0.78 | MAPT (0.40) | BCHEBACE1AHRKEAP1NR3C1 | |
| Hydrochloric Acid SCHEMBL15536131 | 0.77 | AHR (0.54) | JAK2RPS6KA3MELKSTK24BCHE | |
| Ethoxycarbonyl Group SCHEMBL27965810 | 0.77 | PARP1 (0.41) | AHRHDAC3HDAC1CHEK1MAPT | |
| Indole SCHEMBL27375410 | 0.75 | TRPA1 (0.57) | AHRKMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103957910-A | Compounds and methods for enhancing innate immune responses | GLAXOSMITHKLINE LLC | 2014-07-30 | — | — | CN | disclosed |
| CN-103492389-A | Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors | ORIGENIS GMBH | 2014-01-01 | — | — | CN | disclosed |
| CN-101573357-B | Indole compound | TAKAEDA CHEMICAL IND LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101790313-A | Compound (I) | SMITHKLINE BEECHAM CORP | 2010-07-28 | — | — | CN | disclosed |
| CN-101573357-A | Indole compound | TAKEDA PHARMACEUTICAL (JP) | 2009-11-04 | — | — | CN | disclosed |