Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244409 | 0.92 | — | — | |
| SCHEMBL1661734 | 0.76 | TAAR1 (0.48) | LOXL2TAAR1PNMT | |
| SCHEMBL14935619 | 0.71 | — | — | |
| SCHEMBL61982 | 0.71 | — | — | |
| SCHEMBL147803 | 0.71 | — | — | |
| SCHEMBL21194005 | 0.71 | — | — | |
| SCHEMBL28873199 | 0.69 | LOXL2 (0.33) | LOXL2TAAR1 | |
| SCHEMBL921205 | 0.68 | CNR1 (0.39) | — | |
| SCHEMBL1662135 | 0.68 | KDM4E (0.42) | — | |
| SCHEMBL4119633 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778831-A | Novel piperazine amide derivatives | HOFFMANN LA ROCHE | 2010-07-14 | — | — | CN | disclosed |