SCHEMBL27784698

SCHEMBL27784698

COc1cc2c(ccc3cc(OC)c(O)c(OC)c32)cc1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.78
MCL1 Q07820 2/20 0.78
KDM4E B2RXH2 1/20 0.78
ABL1 P00519 1/20 0.78
POLB P06746 1/20 0.78
GAA P10253 1/20 0.78
PKM P14618 1/20 0.78
APEX1 P27695 1/20 0.78
RECQL P46063 1/20 0.78
BLM P54132 1/20 0.78
CDK5 Q00535 1/20 0.78
RIN1 Q13671 1/20 0.78
CDK5R1 Q15078 1/20 0.78
SAE1 Q9UBE0 1/20 0.78
UBA2 Q9UBT2 1/20 0.78
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14439528 0.89 MAPT (0.80) MAPTMCL1KDM4EABL1POLB
SCHEMBL11508300 0.86 MCL1 (0.70) MAPTMCL1KDM4EABL1POLB
SCHEMBL14649604 0.82 MCL1 (0.65) MAPTMCL1KDM4EABL1POLB
SCHEMBL5804721 0.81 MAPT (0.52) MAPTMCL1KDM4EABL1POLB
SCHEMBL27939366 0.81 MAPT (0.52) MAPTMCL1KDM4EABL1POLB
SCHEMBL22978750 0.80 KDM4E (0.58) MAPTMCL1KDM4EABL1POLB
SCHEMBL28864523 0.80 TUBB1 (0.54) MAPTMCL1KDM4EABL1POLB
SCHEMBL11504922 0.79 MAPT (0.85) MAPTMCL1KDM4EABL1POLB
SCHEMBL5808201 0.77 MAPT (0.51) MAPTMCL1KDM4EABL1POLB
SCHEMBL28950290 0.76 TUBB4A (0.69) MAPTMCL1KDM4EABL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101584685-B Pharmaceutical composition for regulating blood fat PINGYA LI 2012-05-23 CN claimed
CN-101584685-A Medicine composition for regulating blood fat PINGYA LI (CN) 2009-11-25 CN claimed
CN-101584685-B Pharmaceutical composition for regulating blood fat PINGYA LI 2012-05-23 CN disclosed
CN-101584685-B Pharmaceutical composition for regulating blood fat PINGYA LI 2012-05-23 CN disclosed
CN-101584685-A Medicine composition for regulating blood fat PINGYA LI (CN) 2009-11-25 CN disclosed
CN-101584685-A Medicine composition for regulating blood fat PINGYA LI (CN) 2009-11-25 CN disclosed