SCHEMBL11508300

SCHEMBL11508300

COc1cc2ccc3cc(O)c(OC)c(OC)c3c2cc1O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.70
KDM4E B2RXH2 2/20 0.70
GAA P10253 2/20 0.70
RECQL P46063 2/20 0.70
MAPT P10636 2/20 0.70
ABL1 P00519 1/20 0.70
POLB P06746 1/20 0.70
PKM P14618 1/20 0.70
APEX1 P27695 1/20 0.70
BLM P54132 1/20 0.70
CDK5 Q00535 1/20 0.70
RIN1 Q13671 1/20 0.70
CDK5R1 Q15078 1/20 0.70
SAE1 Q9UBE0 1/20 0.70
UBA2 Q9UBT2 1/20 0.70
TUBB4A P04350 1/20 0.68
TUBB P07437 1/20 0.68
TUBA3C P0DPH7 1/20 0.68
TUBA1B P68363 1/20 0.68
TUBA4A P68366 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14439528 0.90 MAPT (0.80) MCL1KDM4EGAARECQLMAPT
SCHEMBL27784698 0.86 MAPT (0.78) MCL1KDM4EGAARECQLMAPT
SCHEMBL11504922 0.81 MAPT (0.85) MCL1KDM4EGAARECQLMAPT
SCHEMBL14649604 0.80 MCL1 (0.65) MCL1KDM4EGAARECQLMAPT
SCHEMBL23203427 0.79 TUBB4A (0.55) MCL1KDM4EGAARECQLMAPT
Nudol SCHEMBL3971615 0.79 TUBB4A (0.54) MCL1KDM4EGAARECQLMAPT
SCHEMBL22978750 0.78 KDM4E (0.58) MCL1KDM4EGAARECQLMAPT
SCHEMBL28950290 0.78 TUBB4A (0.69) MCL1KDM4EGAARECQLMAPT
SCHEMBL29833541 0.77 MCL1 (0.57) MCL1KDM4EGAARECQLMAPT
SCHEMBL5804536 0.77 ESR1 (0.51) MCL1KDM4EGAARECQLMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132541-A INHIBITING PLANT GERMINATION AND GROWTH WITH PHENANTHRENE SUBSTITUTED BY CHLORO, HYDROXY, METHOXY AND ACETYL RIKAGAKU KENKYUSHO (JP) 1979-01-02 US claimed
US-4132541-A INHIBITING PLANT GERMINATION AND GROWTH WITH PHENANTHRENE SUBSTITUTED BY CHLORO, HYDROXY, METHOXY AND ACETYL RIKAGAKU KENKYUSHO (JP) 1979-01-02 US disclosed
US-4022842-A PLANT GROWTH REGULATORS RIKAGAKU KENKYUSHO (JA) 1977-05-10 US disclosed
US-3971651-A 9,10-DIHYDROPHENANTHRENES RIKAGAKU KENKYUSHO (JA) 1976-07-27 US disclosed