Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709231 | 0.89 | LCK (0.62) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL9979782 | 0.83 | PTPN11 (0.64) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL29365729 | 0.82 | PTPN11 (0.68) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL69025 | 0.82 | PTPN11 (0.68) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL3018277 | 0.81 | KDM4E (0.59) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL3566353 | 0.81 | CYP2A6 (0.61) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL8732524 | 0.81 | PTPN11 (0.66) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL23909545 | 0.80 | LCK (0.56) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL6414914 | 0.80 | CYP2A6 (0.65) | LCKALOX15HTTPTPN11CA1 | |
| SCHEMBL17829703 | 0.80 | PTPN11 (0.57) | LCKALOX15HTTPTPN11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101595091-A | 1-naphthyl alkylpiperidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-02 | — | — | CN | disclosed |