SCHEMBL27785437

SCHEMBL27785437

O=S(=O)(NCc1ccccn1)c1cc(Br)c2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.53
GAA P10253 2/20 0.52
TSHR P16473 1/20 0.52
ALDH1A1 P00352 3/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 1/20 0.49
ATM Q13315 1/20 0.49
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14712377 0.80 PRMT1 (0.66) PRMT1L3MBTL1GAAALDH1A1LMNA
SCHEMBL18397971 0.79 L3MBTL1 (0.55) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL4482549 0.78 L3MBTL1 (0.58) PRMT1L3MBTL1GAAALDH1A1MEN1
SCHEMBL3925507 0.77 PRMT1 (0.74) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL29530569 0.77 PRMT1 (0.74) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL20267872 0.76 L3MBTL1 (0.65) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL1873887 0.76 PRMT1 (0.77) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL27807434 0.76 L3MBTL1 (0.55) PRMT1L3MBTL1GAATSHRALDH1A1
SCHEMBL9047340 0.76 GAA (0.75) GAATSHRALDH1A1LMNAPOLB
Pyrabactin A SCHEMBL29395044 0.75 L3MBTL1 (0.57) PRMT1L3MBTL1GAATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781244-A Preparation method of 4-bromo-N- (pyridine-2-methyl) naphthalene-1-sulfonamide compound UNIV CHINA AGRICULTURAL 2010-07-21 CN disclosed