Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425459 | 0.89 | GAA (0.80) | GAASMN1; SMN2LMNATSHRHTT | |
| SCHEMBL29531346 | 0.80 | ALDH1A1 (0.78) | GAASMN1; SMN2LMNATSHRHTT | |
| SCHEMBL12793852 | 0.80 | ALDH1A1 (0.78) | GAASMN1; SMN2LMNATSHRHTT | |
| SCHEMBL29530569 | 0.78 | PRMT1 (0.74) | GAAPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL3925507 | 0.78 | PRMT1 (0.74) | GAAPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL20267872 | 0.77 | L3MBTL1 (0.65) | GAALMNATSHRPOLBALDH1A1 | |
| SCHEMBL7421567 | 0.77 | KDM4E (0.63) | GAASMN1; SMN2LMNATSHRHTT | |
| SCHEMBL14712377 | 0.76 | PRMT1 (0.66) | GAAPKMSMN1; SMN2LMNAHTT | |
| SCHEMBL27785437 | 0.76 | PRMT1 (0.55) | GAALMNATSHRPOLBALDH1A1 | |
| SCHEMBL9305676 | 0.75 | PRMT1 (0.74) | GAASMN1; SMN2LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |