Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785894 | 0.81 | RAB9A (0.50) | KDM4EALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL9737555 | 0.77 | NPC1 (0.64) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL8514369 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL1347655 | 0.74 | KDR (0.58) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL6449133 | 0.74 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL6449885 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL6450028 | 0.69 | RAB9A (0.69) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL10835670 | 0.69 | RAB9A (0.55) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL2800972 | 0.69 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL5453348 | 0.68 | RAB9A (0.67) | KDM4EALDH1A1HSD17B10CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224493-A | Novel oxadiazole derivatives and thiadiazole derivatives having neovascularization inhibitory activity | SANTEN PHARMACEUTICAL CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101600712-A | Novel oxadiazole derivative and thiadiazole derivative having angiogenesis inhibitory activity | SANTEN PHARMACEUTICAL CO LTD (JP) | 2009-12-09 | — | — | CN | disclosed |