Trinitrotoluene

Trinitrotoluene

SCHEMBL27786014

CO.Cc1c([N+](=O)[O-])cc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.62
ALDH1A1 P00352 5/20 0.62
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
HPGD P15428 3/20 0.55
MAPK1 P28482 2/20 0.55
CYP1A2 P05177 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TTR P02766 1/20 0.55
MAPT P10636 1/20 0.55
CYP2C9 P11712 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
RECQL P46063 1/20 0.55
PMP22 Q01453 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TSHR P16473 2/20 0.54
HTT P42858 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trinitrotoluene SCHEMBL891182 0.95 ALDH1A1 (0.61) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL20676 0.95 ALDH1A1 (0.61) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL6280179 0.93 GPR35 (0.60) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL9101080 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL9101074 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL2566651 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL14966503 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL28861138 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL1272395 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1
Trinitrotoluene SCHEMBL14966251 0.93 ALDH1A1 (0.59) GPR35ALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108827941-B Method for rapidly detecting TNT in water based on surface enhanced Raman spectroscopy 启东科赛尔纳米科技有限公司 2021-06-18 CN claimed
CN-108827941-A A method of quickly detecting TNT in water based on Surface enhanced Raman spectroscopy 厦门斯贝克科技有限责任公司 2018-11-16 CN claimed
CN-116332946-B Application of tetra (methoxy) anthracene group-containing glycoluril molecular clamp crystal material in TNT recovery 西安近代化学研究所 2024-01-02 CN disclosed
CN-114656409-B Fluorescent material for rapidly detecting explosives, preparation method and application thereof 山东产研绿色与健康研究院有限公司 2023-12-22 CN disclosed
CN-116332946-A Application of tetra (methoxy) anthracene group-containing glycoluril molecular clamp crystal material in TNT recovery 西安近代化学研究所 2023-06-27 CN disclosed
CN-114656409-A Fluorescent material for rapidly detecting explosives and preparation method and application thereof 山东产研绿色与健康研究院有限公司 2022-06-24 CN disclosed
CN-114527104-A Dual-mode fluorescent copper nanocluster for rapid fluorescence detection of trinitrotoluene or trinitrophenol 中国科学院新疆理化技术研究所 2022-05-24 CN disclosed
CN-108827941-B Method for rapidly detecting TNT in water based on surface enhanced Raman spectroscopy 启东科赛尔纳米科技有限公司 2021-06-18 CN disclosed
CN-110687081-A Sensor, preparation method and application thereof, and detection method of 2,4, 6-trinitrophenol 北威(重庆)科技股份有限公司 2020-01-14 CN disclosed
CN-108827941-A A method of quickly detecting TNT in water based on Surface enhanced Raman spectroscopy 厦门斯贝克科技有限责任公司 2018-11-16 CN disclosed
CN-105254853-B Water-dispersible hyperbranched conjugated polymer fluorescent nanoparticles as well as preparation method and application thereof 中国科学院长春应用化学研究所 2017-04-26 CN disclosed
CN-105254853-A Water-dispersible hyperbranched conjugated polymer fluorescent nanoparticles as well as preparation method and application thereof CHANGCHUN APPLIED CHEMISTRY 2016-01-20 CN disclosed
CN-104849258-A Flexible erasable SERS (surface-enhanced Raman scattering) active substrate and preparation method thereof UNIV CHENGDU 2015-08-19 CN disclosed
CN-102183503-A Light irradiation preparation method and use of ultra-sensitive surface enhanced Raman scattering active base HEFEI INST PHYSICAL SCI CAS 2011-09-14 CN disclosed
CN-101597372-B Fluorescent conjugated polymer silicon oxide nanoparticle preparation method and application thereof UNIV ZHEJIANG 2011-01-05 CN disclosed
CN-101597372-A The preparation method and its usage of fluorescent conjugated polymer silicon oxide nanoparticle UNIV ZHEJIANG (CN) 2009-12-09 CN disclosed