Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412677 | 0.77 | NFKB1 (0.47) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL27961586 | 0.74 | NFKB1 (0.45) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| Ammonia Solution, Strong SCHEMBL27340998 | 0.74 | NFKB1 (0.45) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL9464877 | 0.72 | CYP3A4 (0.41) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| Bicarbonate SCHEMBL30411279 | 0.70 | ALDH1A1 (0.48) | CYP3A4BAZ2BADH5 | |
| Biphenyl SCHEMBL27843447 | 0.70 | MEN1 (0.59) | CYP3A4LMNAMAPTNOTUMIDO1 | |
| SCHEMBL27968862 | 0.68 | BCHE (0.35) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL6391242 | 0.67 | POLB (0.59) | CYP3A4MEN1ALOX15TSHRKMT2A | |
| SCHEMBL28283834 | 0.67 | CYP11B1 (0.38) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| Pyridine SCHEMBL28070451 | 0.65 | TSHR (0.43) | CYP3A4MAPTCYP2A6MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600715-A | Compound with angiotensin-ii receptor antagonistic action and PPAR γ activating activities | PFIZER PROD INC (US) | 2009-12-09 | — | — | CN | disclosed |