Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.65 |
| ▸ | HTR1A | P08908 | 6/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.65 |
| ▸ | DRD1 | P21728 | 6/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.65 |
| ▸ | DRD3 | P35462 | 6/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpromazine SCHEMBL18994 | 0.79 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL29354434 | 0.79 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL18993 | 0.79 | CHRM2 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL28795955 | 0.78 | CHRM2 (0.70) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Aminopromazine SCHEMBL25156 | 0.78 | CHRM2 (0.70) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Methylpromazine SCHEMBL2774391 | 0.78 | CHRM2 (0.97) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Aminopromazine SCHEMBL30990818 | 0.78 | CHRM2 (0.70) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Aminopromazine SCHEMBL5307944 | 0.77 | CHRM2 (0.68) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Hydrochloric Acid SCHEMBL28702086 | 0.77 | HTR1A (0.68) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL13611321 | 0.75 | PTGS1 (0.56) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594868-B | Pharmaceutical composition with antipsychotic, antidepressant or antiepileptic activity and reduced side effects | GENE RES LAB INC US N | 2012-12-12 | — | — | CN | disclosed |
| CN-101594868-A | Pharmaceutical composition with antipsychotic, antidepressant or antiepileptic activity and reduced side effects | N GENE RES LAB INC (US) | 2009-12-02 | — | — | CN | disclosed |