Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335791 | 0.77 | MAPT (0.43) | MEN1KMT2AMAPTTSHRATM | |
| SCHEMBL18807015 | 0.77 | PDE10A (0.45) | MEN1KMT2AMAPTTSHRATM | |
| SCHEMBL23162725 | 0.76 | MAPT (0.42) | MEN1KMT2AMAPTTSHRATM | |
| SCHEMBL15921756 | 0.70 | KDM4E (0.53) | MEN1KMT2AMAPTPDE10AALDH1A1 | |
| SCHEMBL1529975 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTTSHRPDE10A | |
| SCHEMBL11272349 | 0.68 | KDM4E (0.41) | MEN1KMT2AMAPTPDE10AALDH1A1 | |
| SCHEMBL18812374 | 0.68 | POLB (0.52) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL6251117 | 0.67 | ADORA2A (0.72) | MEN1KMT2AMAPTTSHRADORA3 | |
| SCHEMBL30353576 | 0.64 | ALDH1A1 (0.58) | MAPTADORA3ALDH1A1KDM4ERAB9A | |
| SCHEMBL863223 | 0.64 | ADORA2A (0.42) | ADORA2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942469-B | Condensed pyridine derivatives useful as A28 adenosine receptor antagonists | ALMIRALL LAB | 2010-07-07 | — | — | CN | disclosed |