Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335791 | 0.84 | MAPT (0.43) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23162725 | 0.83 | MAPT (0.42) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21398283 | 0.80 | ADORA3 (0.55) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27786388 | 0.77 | MEN1 (0.40) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30353595 | 0.77 | ADORA2A (0.50) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15921756 | 0.77 | KDM4E (0.53) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11272349 | 0.74 | KDM4E (0.41) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24689626 | 0.74 | LMNA (0.51) | PDE10AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18812374 | 0.74 | POLB (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL15080589 | 0.73 | MEN1 (0.79) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121357-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121357-A1 | COMPLEXES | CYCS, AP1M1, SOD1 | PDE10A 3390/4885ALDH1A1 1404/4885MEN1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.