SCHEMBL2778639

SCHEMBL2778639

CC(=O)NC(CSCc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.67
PPARA Q07869 6/20 0.62
PPARG P37231 4/20 0.62
PPARD Q03181 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7283024 1.00 ACE (0.67) ACEPPARAPPARGPPARD
SCHEMBL7282451 1.00 ACE (0.67) ACEPPARAPPARGPPARD
SCHEMBL9594476 0.92 ACE (0.58) ACEPPARAPPARGPPARD
SCHEMBL11896626 0.91 ACE (0.56) ACEPPARAPPARGPPARD
SCHEMBL13870212 0.88 ACE (0.68) ACEPPARAPPARG
SCHEMBL27258933 0.87 ACE (0.55) ACEPPARAPPARG
SCHEMBL12537197 0.87 ACE (0.55) ACEPPARAPPARGPPARD
SCHEMBL14544522 0.87 MAPT (0.54) ACEPPARAPPARGPPARD
SCHEMBL11555486 0.87 ACE (0.69) ACEPPARAPPARGPPARD
SCHEMBL20817462 0.87 ACE (0.69) ACEPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240159775-A1 WASTEWATER-BASED EPIDEMIOLOGY METHODS FOR ASSESSING POPULATION HEALTH ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-05-16 US claimed
CN-116148368-A Method for detecting various environmental pollutants and oxidative damage markers in urine 华中科技大学 2023-05-23 CN claimed
US-4002671-A REDUCE SEBUM SECRETION ON SCALP OR SKIN SOCIETE ANONYME DITE: L'OREAL (FR) 1977-01-11 US claimed
US-20240159775-A1 WASTEWATER-BASED EPIDEMIOLOGY METHODS FOR ASSESSING POPULATION HEALTH ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-05-16 US disclosed
US-11464784-B2 Inhibition of aminocylase 3 (AA3) in the treatment of cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-11 US disclosed
US-20200206239-A1 INHIBITION OF AMINOCYLASE 3 (AA3) IN THE TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-07-02 US disclosed
US-20190346449-A1 BTEX METABOLITES DERIVATIZATION KIT AND COMPOSITION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2019-11-14 US disclosed
WO-2019055825-A1 INHIBITION OF AMINOACYLASE 3 (AA3) IN THE TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-03-21 WO disclosed
US-8227687-B2 Quantum dot solar cell HONEYWELL INTERNATIONAL INC. (US) 2012-07-24 US disclosed
EP-2216839-A2 Quantum dot solar cell Honeywell International Inc. (US) 2010-08-11 EP disclosed
EP-2216839-A2 Quantum dot solar cell Honeywell International Inc. (US) 2010-08-11 EP disclosed
EP-0213785-A1 Method for optical resolution of DL-cysteine and (R,S)-1-(1-naphthyl)ethylamine NIPPON RIKAGAKUYAKUHIN CO., LTD. (JP) 1987-03-11 EP disclosed
US-4394520-A SKIN DISORDERS SOCIETE ANONYME DITE: L'OREAL (FR) 1983-07-19 US disclosed
US-4204064-A FOR TREATMENT OF SKIN OR SCALP L'OREAL (FR) 1980-05-20 US disclosed
US-4151301-A ANTISECRETORY L'OREAL (FR) 1979-04-24 US disclosed
US-4139635-A Cysteamine derivatives for oral treatment of seborrhea L'OREAL (FR) 1979-02-13 US disclosed
US-4085217-A DERIVATIVES OF CYSTEINE OR CYSTEAMINE L'OREAL (FR) 1978-04-18 US disclosed
US-4002671-A REDUCE SEBUM SECRETION ON SCALP OR SKIN SOCIETE ANONYME DITE: L'OREAL (FR) 1977-01-11 US disclosed
US-3976781-A SULFUR CONTAINING AMINES L'OREAL (FR) 1976-08-24 US disclosed
US-3950542-A Cysteamine derivatives for oral treatment of seborrhea L'OREAL (FR) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206239-A1 INHIBITION OF AMINOCYLASE 3 (AA3) IN THE TREATMENT OF CANCER PLAAT3, HCCS, LAP3 ACE 836/4885PPARA 1777/4885PPARG 1762/4885
US-11464784-B2 Inhibition of aminocylase 3 (AA3) in the treatment of cancer PLAAT3, HCCS, LAP3 ACE 836/4885PPARA 1777/4885PPARG 1762/4885
US-20190346449-A1 BTEX METABOLITES DERIVATIZATION KIT AND COMPOSITION BTD, BTF3, PTMS ACE 989/4885PPARA 3390/4885PPARG 2219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.