Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786394 | 0.88 | HSD11B1 (0.42) | HSD11B1AVPR1ACNR1KCNH2 | |
| SCHEMBL829077 | 0.86 | AVPR1A (0.49) | HSD11B1AVPR1ACNR1KCNH2OPRM1 | |
| SCHEMBL828756 | 0.86 | AVPR1A (0.47) | HSD11B1AVPR1ACNR1OPRM1OPRK1 | |
| SCHEMBL825148 | 0.84 | AVPR1A (0.59) | HSD11B1AVPR1ACNR1OPRM1OPRK1 | |
| SCHEMBL825327 | 0.83 | AVPR1A (0.47) | HSD11B1AVPR1ACNR1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL829428 | 0.83 | AVPR1A (0.46) | HSD11B1AVPR1ACNR1OPRM1OPRK1 | |
| SCHEMBL825277 | 0.82 | OXTR (0.49) | HSD11B1AVPR1A | |
| SCHEMBL825146 | 0.81 | OXTR (0.50) | HSD11B1AVPR1ACNR1OPRM1OPRK1 | |
| SCHEMBL825145 | 0.81 | AVPR1A (0.50) | HSD11B1AVPR1ACNR1KCNH2 | |
| SCHEMBL825238 | 0.81 | AVPR1A (0.59) | HSD11B1AVPR1ACNR1KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101583609-A | Indoles | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | CN | disclosed |