Morpholine

Morpholine

SCHEMBL27786409

C1COCCN1.Cc1cc(Cl)cc(C=O)c1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 15/20 0.50
HRH4 Q9H3N8 1/20 0.35
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
PRKDC P78527 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954242 0.83 ERN1 (0.72) ERN1
SCHEMBL2298759 0.83 ERN1 (0.72) ERN1
Morpholine SCHEMBL27786411 0.71 ESR2 (0.44) LMNAGAAMAPTMAPK1TDP1
SCHEMBL6093685 0.70 ERN1 (1.00) ERN1TDP1
SCHEMBL15459923 0.69 PTGS1 (0.47) ERN1MAPTMEN1KMT2A
SCHEMBL14876731 0.66 ERN1 (0.54) ERN1MAPTTDP1MEN1KMT2A
Salicyladehyde SCHEMBL27901835 0.66 TRIM24 (0.62) ERN1LMNAGAAMAPTTDP1
SCHEMBL2788053 0.65 ERN1 (0.78) ERN1LMNAGAAMAPTMEN1
SCHEMBL29382880 0.65 ERN1 (1.00) ERN1LMNAMAPTMAPK1TDP1
SCHEMBL30689082 0.65 ERN1 (0.78) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781231-B Ethylene oligomerization catalyst, preparation method and usage thereof CHINA PETROLEUM & CHEMICAL 2013-08-28 CN disclosed
CN-101781231-A Ethylene oligomerization catalyst, preparation method and usage thereof CHINA PETROLEUM & CHEMICAL 2010-07-21 CN disclosed