Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.72 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954242 | 1.00 | ERN1 (0.72) | ERN1PIM1ALOX5PTGS1PTGS2 | |
| SCHEMBL6093685 | 0.84 | ERN1 (1.00) | ERN1PIM1CYP3A4 | |
| Morpholine SCHEMBL27786409 | 0.83 | ERN1 (0.50) | ERN1 | |
| SCHEMBL15459923 | 0.83 | PTGS1 (0.47) | ERN1ALOX5PTGS1PTGS2CYP1A2 | |
| SCHEMBL14876731 | 0.80 | ERN1 (0.54) | ERN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2788053 | 0.78 | ERN1 (0.78) | ERN1PIM1ALOX5PTGS1PTGS2 | |
| SCHEMBL30689082 | 0.78 | ERN1 (0.78) | ERN1PIM1 | |
| SCHEMBL29957335 | 0.78 | ERN1 (0.78) | ERN1PIM1ALOX5PTGS1PTGS2 | |
| SCHEMBL29382880 | 0.78 | ERN1 (1.00) | ERN1CYP3A4 | |
| SCHEMBL456670 | 0.78 | ERN1 (0.78) | ERN1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102924425-B | Homopiperony lamine 3-methyl-5-chlorine salicylide and synthesis method and application thereof | UNIV GUANGXI NORMAL | 2014-05-28 | — | — | CN | claimed |
| CN-102924425-A | Homopiperony lamine 3-methyl-5-chlorine salicylide and synthesis method and application thereof | UNIV GUANGXI NORMAL | 2013-02-13 | — | — | CN | claimed |
| CN-118184844-A | Preparation method of special resin for high-strength polyethylene film | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184834-A | Ziegler-Natta catalyst for ethylene polymerization | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184833-A | Phenolic amine type internal electron donor composition for ethylene polymerization catalyst and preparation method thereof | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117101726-A | Metal complex catalyst and preparation method of 2, 4-trimethyl adipic acid | 山东新和成维生素有限公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-3625227-B1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-14 | — | — | EP | disclosed |
| US-11325899-B2 | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-05-10 | — | — | US | disclosed |
| US-20210115031-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-04-22 | — | — | US | disclosed |
| EP-3625227-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | disclosed |
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |
| EP-0018939-A1 | 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs | CIBA-GEIGY AG (CH) | 1980-11-12 | — | — | EP | disclosed |
| US-4219473-A | Substituted unsymmetrical azo, azomethine 1:2 chromium complexes | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4215042-A | PRINTING AND DYEING OF POLYAMIDES; COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| EP-0009466-A1 | 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use | CIBA-GEIGY AG (CH) | 1980-04-02 | — | — | EP | disclosed |
| EP-0005207-A2 | Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather | CIBA-GEIGY AG (CH) | 1979-11-14 | — | — | EP | disclosed |
| US-4116952-A | POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4086223-A | Asymmetrical 1:2-chromium complex azo dyestuffs | CIBA-GEIGY AG (CH) | 1978-04-25 | — | — | US | disclosed |
| US-4033942-A | Chromium complex dye, including azo and azo methine dye compounds | CIBA-GEIGY AG (CH) | 1977-07-05 | — | — | US | disclosed |
| US-3978037-A | POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115031-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER4, PTGER1, PTGER2 | ERN1 1627/4885PIM1 3327/4885ALOX5 85/4885 |
| US-11325899-B2 | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators | PTGER4, PTGER1, PTGER2 | ERN1 1627/4885PIM1 3327/4885ALOX5 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.