SCHEMBL6093685

SCHEMBL6093685

O=Cc1cc(Cl)cc(C=O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 14/20 1.00
PIM1 P11309 1/20 0.47
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382880 0.88 ERN1 (1.00) ERN1TDP1ALDH1A1CYP3A4TSHR
SCHEMBL294059 0.88 ERN1 (1.00) ERN1TDP1ALDH1A1CYP3A4TSHR
SCHEMBL30689082 0.88 ERN1 (0.78) ERN1PIM1
SCHEMBL456670 0.88 ERN1 (0.78) ERN1PIM1
SCHEMBL27998889 0.86 ERN1 (0.96) ERN1TDP1ALDH1A1CYP3A4TSHR
SCHEMBL29956081 0.86 ERN1 (0.75) ERN1
SCHEMBL28337241 0.86 ERN1 (0.96) ERN1TDP1ALDH1A1CYP3A4TSHR
SCHEMBL3664243 0.86 ERN1 (0.75) ERN1
SCHEMBL30294924 0.86 ERN1 (0.96) ERN1TDP1ALDH1A1CYP3A4TSHR
SCHEMBL3207260 0.84 ERN1 (0.72) ERN1PIM1TDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388787-A Preparation of Salamo type copper (II) semiconductor polymer and method for converting macromolecule into micromolecule 兰州交通大学 2024-07-26 CN claimed
CN-113801100-B Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-05-06 CN claimed
CN-113845535-B Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-03-08 CN claimed
CN-113845535-A Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-28 CN claimed
CN-113801100-A Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-17 CN claimed
CN-101417961-A Anion receptor based on nitro phenylhydrazone and phenolic hydroxyl and preparation of anion test paper and use thereof UNIV NORTHWEST NORMAL (CN) 2009-04-29 CN claimed
EP-1386603-A1 Use of diamines having at least one quaternised group and dialdehydes for dyeing keratin fibres L'OREAL (FR) 2004-02-04 EP claimed
CN-119954759-A Benzopyran COX-2 inhibitor and application thereof 安炎达医药技术(广州)有限公司 2025-05-09 CN disclosed
CN-118388787-A Preparation of Salamo type copper (II) semiconductor polymer and method for converting macromolecule into micromolecule 兰州交通大学 2024-07-26 CN disclosed
CN-114621408-B Solid polymer electrolyte 北京大学 2023-03-31 CN disclosed
CN-114621408-A Solid polymer electrolyte 北京大学 2022-06-14 CN disclosed
CN-113801100-B Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-05-06 CN disclosed
CN-113845535-B Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-03-08 CN disclosed
EP-0656362-B1 Macrocyclic compounds and their use as pharmaceuticals LILLY CO ELI (GB) 1999-09-01 EP disclosed
WO-1998047890-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-10-29 WO disclosed
US-5580900-A TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEM LILLY INDUSTRIES LIMITED (GB) 1996-12-03 US disclosed
US-5574158-A CRYPT COMPOUNDS, NERVOUS SYSTEM DISORDERS, CHELATE COMPOUNDS LILLY INDUSTRIES LIMITED (GB) 1996-11-12 US disclosed
US-5428065-A Treating central nervous system disorders LILLY INDUSTRIES LIMITED (GB) 1995-06-27 US disclosed
EP-0656362-A1 Novel compounds LILLY INDUSTRIES LIMITED (GB) 1995-06-07 EP disclosed
EP-0645370-A1 Substituted m-xylylene diamines for the treatment of diseases of the central nervous system LILLY INDUSTRIES LIMITED (GB) 1995-03-29 EP disclosed