Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786505 | 0.85 | CSNK1D (0.40) | TACR1ALDH1A1TDP1 | |
| SCHEMBL27764701 | 0.79 | ADRA2B (0.37) | TACR1ADRA2BCCR1ALDH1A1MAPT | |
| SCHEMBL27786498 | 0.78 | TRPV1 (0.34) | ADRA2BALDH1A1MAPT | |
| Tert-Butyl Formate SCHEMBL27786503 | 0.77 | CYP1A2 (0.39) | ADRA2BALDH1A1 | |
| SCHEMBL27764680 | 0.73 | CSNK1D (0.41) | ALDH1A1TDP1 | |
| SCHEMBL27786492 | 0.72 | SLC6A9 (0.45) | ALDH1A1MAPT | |
| SCHEMBL27994092 | 0.71 | POLB (0.33) | ALDH1A1MAPTTDP1 | |
| SCHEMBL2964733 | 0.71 | SMARCA2 (0.49) | TACR1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL27648857 | 0.70 | TRPV1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL2958371 | 0.69 | CKS1B (0.55) | SMARCA2SMARCA4PBRM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605764-B | Fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2013-06-19 | — | — | CN | disclosed |
| CN-101605764-A | Fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-16 | — | — | CN | disclosed |