Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910495 | 0.92 | SLC1A3 (0.50) | TACR1CYP1A2CYP2A6RAB9ASLC1A3 | |
| SCHEMBL28413975 | 0.86 | CYP1A2 (0.52) | GAATACR1CYP1A2CYP2A6RAB9A | |
| Hydrochloric Acid SCHEMBL27504503 | 0.84 | CYP1A2 (0.50) | GAATACR1CYP1A2CYP2A6RAB9A | |
| SCHEMBL6910501 | 0.84 | CYP1A2 (0.51) | TACR1CYP1A2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4781267 | 0.84 | GAA (0.51) | GAACYP1A2CYP2A6CNR2 | |
| SCHEMBL3800271 | 0.83 | GAA (0.56) | GAACYP1A2CYP2A6RAB9A | |
| SCHEMBL21652695 | 0.82 | MGAM (0.62) | GAAMGAMSIMGAM2 | |
| SCHEMBL4137536 | 0.81 | GAA (0.49) | GAACYP1A2CYP2A6RAB9ACNR2 | |
| SCHEMBL1557559 | 0.80 | ALDH1A1 (0.61) | GAAMGAMSIMGAM2RAB9A | |
| SCHEMBL2385413 | 0.80 | CYP4F2 (0.59) | GAACYP1A2CYP2A6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-B | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |