SCHEMBL6910495

SCHEMBL6910495

O=C(CC(=O)OCc1ccc2ccccc2c1)OCc1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
TACR1 P25103 1/20 0.48
RAB9A P51151 1/20 0.47
CYP1A2 P05177 2/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
NLRP3 Q96P20 1/20 0.47
CASP1 P29466 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP2A6 P11509 1/20 0.46
ALOX5 P09917 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27787124 0.92 GAA (0.52) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL6910501 0.92 CYP1A2 (0.51) SLC1A3SLC1A2SLC1A1TACR1CYP1A2
SCHEMBL9411099 0.86 PTPN1 (0.49) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL5215830 0.86 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL28413975 0.86 CYP1A2 (0.52) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL28936084 0.85 CYP1A2 (0.54) SLC1A3SLC1A2SLC1A1TACR1RAB9A
Hydrochloric Acid SCHEMBL27504503 0.85 CYP1A2 (0.50) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL6443298 0.84 SLC1A3 (0.55) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL6443296 0.84 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1TACR1RAB9A
SCHEMBL10356778 0.83 RAB9A (0.47) SLC1A3SLC1A2SLC1A1TACR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0813554-B1 METHOD FOR PRODUCING A PREPOLYMERIZED CATALYST EXXONMOBIL CHEM PATENTS INC (US) 2004-04-07 EP disclosed
US-6010588-A MELT PROCESSING USING CATALYST; FORMING FIBER; DRAWING EXXON CHEMICAL PATENTS INC. (US) 2000-01-04 US disclosed
WO-1994028034-A9 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC (US) 1999-07-29 WO disclosed
EP-0758355-B1 APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF EXXON CHEMICAL PATENTS INC (US) 1998-12-09 EP disclosed
EP-0854212-A1 Novel polyolefin fibers and their fabrics EXXON CHEMICAL PATENTS INC. (US) 1998-07-22 EP disclosed
US-5736465-A ONE STEP CATALYTIC POLYMERIZED POLYPROPYLENE; AIR PERMEABILITY; FILTERS EXXON CHEMICAL PATENTS INC. (US) 1998-04-07 US disclosed
US-5723217-A MOLECULAR WEIGHT EXXON CHEMICAL PATENTS INC. (US) 1998-03-03 US disclosed
EP-0813554-A1 METHOD FOR PRODUCING A PREPOLYMERIZED CATALYST EXXON CHEMICAL PATENTS INC. (US) 1997-12-29 EP disclosed
EP-0739346-A1 USE OF GEL-FREE ALUMOXANE SOLUTION EXXON CHEMICAL PATENTS INC. (US) 1996-10-30 EP disclosed
WO-1996028479-A1 METHOD FOR PRODUCING A PREPOLYMERIZED CATALYST EXXON CHEMICAL PATENTS INC. (US) 1996-09-19 WO disclosed
EP-0700464-A1 NOVEL POLYOLEFIN FIBERS AND THEIR FABRICS EXXON CHEMICAL PATENTS INC. (US) 1996-03-13 EP disclosed
US-5468440-A Forming structure from polypropylene resin produced using metallocene catalyst, orienting structure by applying stress at temperature 20-35 degrees C. above Heat Distortion Test value of polypropylene EXXON CHEMICAL PATENTS INC. (US) 1995-11-21 US disclosed
WO-1995018809-A1 USE OF GEL-FREE ALUMOXANE SOLUTION EXXON CHEMICAL PATENTS INC. (US) 1995-07-13 WO disclosed
WO-1994028219-A1 NOVEL POLYOLEFIN FIBERS AND THEIR FABRICS EXXON CHEMICAL PATENTS INC. (US) 1994-12-08 WO disclosed
US-5262436-A Administering; enzyme inhibitor SCHERING CORPORATION (US) 1993-11-16 US disclosed
EP-0566157-A1 Neutral metalloendopeptidase inhibitors in the treatment of hypertension SCHERING CORPORATION (US) 1993-10-20 EP disclosed
US-5061710-A Atrial natriuretic factors SCHERING CORPORATION (US) 1991-10-29 US disclosed
US-4929641-A DIURETICS, ANGIOTENSIN CONVERTING ENZYMES SCHERING CORPORATION (US) 1990-05-29 US disclosed
US-4801609-A Mercapto-acylamino acid antihypertensives SCHERING CORPORATION (US) 1989-01-31 US disclosed
EP-0254032-A2 Neutral metalloendopeptidase inhibitors in the treatment of hypertension SCHERING CORPORATION (US) 1988-01-27 EP disclosed