Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.63 |
| ▸ | NPC1 | O15118 | 12/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910747 | 0.81 | KMT2A (0.61) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL7718028 | 0.80 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL1455288 | 0.80 | MAPT (0.76) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL28187946 | 0.79 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL18086518 | 0.78 | HDAC3 (0.67) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29878091 | 0.78 | GRM4 (0.54) | KMT2ABACE1 | |
| SCHEMBL12010995 | 0.78 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL11903751 | 0.77 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL4191155 | 0.77 | GAA (0.62) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL1454424 | 0.77 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594871-A | Pyrrolopyrimidine compounds and uses thereof | NOVARTIS AG (CH) | 2009-12-02 | — | — | CN | disclosed |