Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933302 | 0.74 | CYP4A11 (0.50) | POLBALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11896606 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2069111 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL225815 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17466182 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11896235 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL223238 | 0.73 | TDP1 (0.96) | TDP1F2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1858708 | 0.73 | ALDH1A1 (0.45) | F2PLAUKLKB1ELANEPOLB | |
| SCHEMBL1863547 | 0.73 | ALDH1A1 (0.45) | F2PLAUKLKB1ELANEPOLB | |
| SCHEMBL30395994 | 0.73 | TDP1 (0.69) | TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541756-A | Pyrazoles as glucokinase activators | HOFFMANN LA ROCHE (CH) | 2009-09-23 | — | — | CN | disclosed |