Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374412 | 0.87 | ALDH1A1 (0.49) | TSHRMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL5866590 | 0.76 | ALDH1A1 (0.51) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27579834 | 0.75 | KMT2A (0.52) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| Dinitrophenylene SCHEMBL27494788 | 0.75 | TSHR (0.65) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28255785 | 0.74 | ALDH1A1 (0.50) | KMT2AMAPTCTSVCTSLALDH1A1 | |
| SCHEMBL11664059 | 0.74 | MAPT (0.49) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL772921 | 0.73 | ALOX15 (0.52) | TSHRKMT2AMAPTADRB2ADRB1 | |
| SCHEMBL1531391 | 0.73 | HTT (0.53) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL12429752 | 0.73 | HTT (0.53) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL1531395 | 0.73 | HTT (0.53) | MEN1KMT2AMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801938-A | Non-basic melanin concentrating hormone receptor body-1 antagonist and method | BRISTOL MYERS SQUIBB CO | 2010-08-11 | — | — | CN | disclosed |