Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.56 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809392 | 0.93 | EGFR (0.51) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL28798414 | 0.88 | EGFR (0.54) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL27858209 | 0.88 | EGFR (0.54) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| Lysine SCHEMBL27787482 | 0.87 | EGFR (0.43) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL27787480 | 0.86 | EGFR (0.74) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL27770270 | 0.82 | EGFR (0.60) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| Lysine SCHEMBL27787481 | 0.81 | CA1 (0.41) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL28787539 | 0.79 | EGFR (0.51) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL11241726 | 0.77 | CA1 (0.65) | EGFRNOX4ALDH1A1MAPTTDP1 | |
| SCHEMBL25027 | 0.76 | CFD (0.73) | ALDH1A1TDP1KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102516107-A | N-benzylaniline derivatives and application thereof | UNIV NANJING MEDICAL | 2012-06-27 | — | — | CN | disclosed |
| CN-101792399-A | Aminosalicylic acid derivative lysine complex salt, preparation method and application thereof | UNIV NANJING MEDICAL | 2010-08-04 | — | — | CN | disclosed |